Kalsiumravinteissa piilee huomattava sydänkohtausriski

[Julkkikset Team]

Kalsiumtabletteja käytetään yleisesti voimistamaan luustoa.

Kansainvälinen tutkijaryhmä teki kliinisiä kokeita yhteensä 12 000 potilaalle neljän vuoden aikana. Kalsiumravinteilla on tutkimustulosten mukaan yhteys myös aivohalvauksiin ja kuolemiin, kuitenkin paljon vähemmän kuin sydänkohtauksiin.

- Ihmiset pitävät kalsiumlisäravinteita luonnollisina, mutta ne eivät ole luonnollisia alkuunkaan,

http://www.mtv3.fi/uutiset/ulkomaat.shtml/arkistot/ulkomaat/2010/07/1163899

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http://aje.oxfordjournals.org/cgi/content/abstract/149/2/151

These results suggest that a higher intake of calcium, but not of vitamin D or milk products, is associated with reduced ischemic heart disease mortality in postmenopausal women, and reduced risk may be achievable whether the higher intake of calcium is attained by diet, supplements, or both. Am J Epidemiol 1999;149:151–61.

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http://www.mayoclinic.com/health/calcium-supplements/AN01928

Over the years, many studies have suggested that women who have a higher calcium intake experience not only improved bone health but also a lower risk of cardiovascular disease. One recent study, however, raised questions about the protective effect of calcium supplements on cardiovascular disease.

The study — which was published February 2008 in BMJ — was done primarily to evaluate the effect of calcium supplementation on bone density and bone fracture in elderly women. Later, however, the results were reanalyzed to note the occurrence of cardiac events among study participants. Although more heart attacks occurred in women who took calcium supplements, the statistical analysis indicated that the difference could have been due to chance. Also, a similar placebo-controlled study of calcium supplementation showed no increase in the risk of heart attack or other cardiovascular disease in women taking calcium.

Current recommendations regarding calcium supplementation haven't changed because of this study. As with any health issue, it's important to consult your doctor to determine what's best in your case. Many factors may influence your specific needs for calcium.

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Huomattavaa myös, että tuo tutkimuksessa löydetty riski koski vain vanhempia naisia, joilla oli sydänongelmia, ja silti se oli aika pieni riski.

http://www.healthfinder.gov/news/newsstory.aspx?docID=641629

"The increased risk for a heart attack was a modest one, the researchers noted."

"It is not clear whether they really increase the risk of heart attacks or strokes," he said. "However, they do appear to be a waste of time and effort, and we should probably stop using them."

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http://www.amjmed.com/article/S0002-9343(99)80310-6/abstract

conclusions
Calcium supplementation produces a sustained reduction in the rate of loss of total body BMD in healthy postmenopausal women

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http://www.ajcn.org/cgi/content/abstract/77/4/814

Conclusion: The results suggest that neither dietary nor supplemental intakes of calcium are appreciably associated with the risk of IHD among men.

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tässä joku aiempi tutkimus:

http://www.bmj.com/cgi/content/abstract/336/7638/262

Conclusion Calcium supplementation in healthy postmenopausal women is associated with upward trends in cardiovascular event rates. This potentially detrimental effect should be balanced against the likely benefits of calcium on bone.

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Eipä tuota kalsiumia itse ole tullut kyllä suuria annoksia otettua. Suomalainen suositus on aika korkea. Mitenkähän, jos kalsiumpillerin sekoittaa vaikka pirtelöön. Käyttäytyyköhän se silloin luonnollisen kalsiumin tavoin, kun on ruokaan sekoittunut...

Concerns and Cautions:
Experts recommend that intake from food and supplements combined should not exceed 2,500 milligrams a day.

Even at more typical dosages ranging from 1,000 mg to 1,200 mg daily, increased intake of calcium has been associated with increased prostate cancer risk.

A recent analysis of results pooled from a number of clinical trials showed a 30% increase in the risk of heart attack among adults taking calcium supplements compared to those who did not. A small, non-significant increase in the risk of stroke and death was also noted. The risk of heart attack with calcium supplementation tended to be greater in people with dietary calcium intake above 805 mg per day. However, calcium intake from foods alone, such as dairy, was not associated with increased cardiovascular risk, consistent with findings from other studies. The study did not evaluate the effects of calcium given with vitamin D (Bolland, British Medical Journal 2010).

Taking too much calcium during pregnancy might potentially cause abnormalities in the fetus.

Calcium supplements can impair the absorption of thyroid hormone as well as antibiotics in the fluroquinolone (e.g., Cipro) and tetracycline families.

For more information see the article about calcium in the Natural Products Encyclopedia on this Web site. Also see the government report on vitamin D at http://ods.od.nih.gov/factsheets/vitamind.asp.

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http://www.iltalehti.fi/terveys/2010080512146174_tr.shtml

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Huomattavaa myös, että tuo tutkimuksessa löydetty riski koski vain vanhempia naisia, joilla oli sydänongelmia, ja silti se oli aika pieni riski.

http://www.healthfinder.gov/news/newsstory.aspx?docID=641629

"The increased risk for a heart attack was a modest one, the researchers noted."

"It is not clear whether they really increase the risk of heart attacks or strokes," he said. "However, they do appear to be a waste of time and effort, and we should probably stop using them."

Eui toi 30% kyllä ole kauhean pieni.

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http://www.bmj.com/cgi/content/full/341/jul29_1/c3691?maxtoshow=&hits=10&RESULTFORMAT=&fulltext

Tuossa vielä tuo alkuperäinen tutkimus.